LGAI-EXAONE / EXAONEPath-CRC-MSI-Predictor

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Model's Last Updated: February 18 2025

Introduction of EXAONEPath-CRC-MSI-Predictor

Model Details of EXAONEPath-CRC-MSI-Predictor

Description

MSI classification of CRC tumors using EXAONEPath 1.0.0 - a patch-level foundation model for pathology

Model Overview

This model serves as a reference for predicting MSI status using CRC (colorectal cancer) tumor images as input. When the model receives an H&E-stained whole slide image as input, it removes artifacts observed in the image and extracts only tissue-related objects. These objects are then reconstructed into a set of tiles with a size of 256 by 256 pixels at an mpp (micron per pixel) of 0.5.

The tiles pass through the EXAONEPath v1.0 patch-level foundation model ( https://huggingface.co/LGAI-EXAONE/EXAONEPath ), which converts them into a set of features. These features are then integrated into a slide-level feature representation through an aggregator. Finally, a linear classifier predicts the MSI status (MSS or MSI-H/L).

The model achieves an average performance of AUROC 0.93 on TCGA-COAD + TCGA-READ data and 0.84 on in-house data.

This open-source release aims to demonstrate that the combination of EXAONEPath and the aggregator can effectively perform pathological tasks. It is hoped that this source code will serve as an important reference not only for CRC MSI prediction but also as an image-based solution for various disease-related problems, including molecular subtyping, tumor subtyping, and mutation prediction.

This open-source code is designed to be compatible with the MONAI framework ( https://monai.io/ ), and users must check the accompanying license before use.

EXAONEPath

Input and Output Formats

The input is a .svs file containing whole slide image. The output is an array with probabilities for each of the two classes (MSS / MSI(H/L)).

Setup

pip install -r requirements.txt

Execute Inference

The inference can be executed as follows

  1. Copy your .svs files into samples directory
  2. Run inference
    python -m monai.bundle run inference --meta_file configs/metadata.json --config_file configs/inference.yaml
    
Contact

LG AI Research Technical Support: [email protected]

License

Copyright (c) LG AI Research

The model is licensed under EXAONEPath AI Model License Agreement 1.0 - NC .

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https://choosealicense.com/licenses/exaonepath

EXAONEPath-CRC-MSI-Predictor huggingface.co

EXAONEPath-CRC-MSI-Predictor huggingface.co is an AI model on huggingface.co that provides EXAONEPath-CRC-MSI-Predictor's model effect (), which can be used instantly with this LGAI-EXAONE EXAONEPath-CRC-MSI-Predictor model. huggingface.co supports a free trial of the EXAONEPath-CRC-MSI-Predictor model, and also provides paid use of the EXAONEPath-CRC-MSI-Predictor. Support call EXAONEPath-CRC-MSI-Predictor model through api, including Node.js, Python, http.

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https://huggingface.co/LGAI-EXAONE/EXAONEPath-CRC-MSI-Predictor

LGAI-EXAONE EXAONEPath-CRC-MSI-Predictor online free

EXAONEPath-CRC-MSI-Predictor huggingface.co is an online trial and call api platform, which integrates EXAONEPath-CRC-MSI-Predictor's modeling effects, including api services, and provides a free online trial of EXAONEPath-CRC-MSI-Predictor, you can try EXAONEPath-CRC-MSI-Predictor online for free by clicking the link below.

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https://huggingface.co/LGAI-EXAONE/EXAONEPath-CRC-MSI-Predictor

EXAONEPath-CRC-MSI-Predictor install

EXAONEPath-CRC-MSI-Predictor is an open source model from GitHub that offers a free installation service, and any user can find EXAONEPath-CRC-MSI-Predictor on GitHub to install. At the same time, huggingface.co provides the effect of EXAONEPath-CRC-MSI-Predictor install, users can directly use EXAONEPath-CRC-MSI-Predictor installed effect in huggingface.co for debugging and trial. It also supports api for free installation.

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Updated:September 18 2025