A powerful tool for searching and exploring community-driven protein mutation analysis and AlphaFold2 folding results.
Install & Download
1. ClawHub CLI
The fastest way to install a skill directly from the registry.
npx clawhub@latest install clarity-research
2. Manual Installation
Copy the skill folder to one of these locations
~/.openclaw/skills/ <project>/skills/ Priority: Workspace > Local > Bundled
3. Prompt Installation
Copy this prompt to OpenClaw to install it automatically.
Help me install clarity-research using Clawhub. If Clawhub is not installed, install it first (npm i -g clawhub).
Prefer to download?
Get the raw skill files in a ZIP archive.
What is Clarity Research?
The Clarity Research skill provides seamless integration with the Clarity Protocol, a community-driven platform dedicated to protein mutation analysis. By leveraging AlphaFold2 data via ColabFold, this skill allows users to query vast datasets of protein variants and fold results. It is an essential addition to Openclaw Skills for researchers and developers working on bioinformatics, disease-specific protein data, and mutation impacts.
This skill enables users to explore protein research data with high precision, offering access to confidence scores, UniProt identifiers, and disease associations. Whether you are investigating Alzheimer's or searching for specific protein mutations like MAPT, this skill streamlines the process of data retrieval and analysis.
Clarity Research Use Cases
- Search for protein variants associated with specific diseases like Alzheimer's.
- Explore AlphaFold2 folding results and confidence scores for various protein mutations.
- Identify specific fold IDs for deeper structural analysis in external tools.
- Retrieve comprehensive overviews of protein research data available within the Clarity Protocol.
- Automate the discovery of protein variants for bioinformatics pipelines using Openclaw Skills.
How Clarity Research Works
- The skill connects to the Clarity Protocol API to query the protein folding database.
- Users specify search parameters such as disease name or protein name through command-line flags.
- The skill handles API authentication using an optional CLARITY_API_KEY to increase throughput.
- It processes paginated results automatically using the next_cursor field to ensure full data retrieval.
- Structured protein data, including UniProt IDs and AlphaFold confidence scores, is returned for analysis.
Clarity Research Setup
To get started with this skill, ensure you have internet access. While an API key is optional, it is recommended for higher rate limits.
Install the necessary dependencies and run the query script:
python scripts/query_variants.py --disease Alzheimer
To increase your rate limit to 100 requests per minute, set your API key:
export CLARITY_API_KEY=your_key_here
python scripts/query_variants.py --protein-name MAPT
You can acquire an API key from the Clarity Protocol homepage. These steps make it easy to integrate research capabilities into your Openclaw Skills library.
Clarity Research Data Schema & Taxonomy
The skill organizes protein research data into a structured format containing the following fields:
| Field | Description |
|---|---|
| id | Unique identifier for the specific protein fold. |
| protein_name | Common name of the protein (e.g., tau, APP). |
| variant | Mutation notation (e.g., P301L, A246E). |
| disease | The disease associated with the mutation. |
| uniprot_id | Identifier for the UniProt database. |
| average_confidence | The AlphaFold2 confidence score (range 0-100). |
| created_at | Timestamp of when the fold was generated. |
This schema ensures consistency when using these Openclaw Skills for data mining.
Clarity Research Advanced Features
- Automatic pagination handling via next_cursor for large research datasets.
- Enhanced rate limiting (up to 100 req/min) with API key integration.
- Robust error handling for timeouts and API-specific response codes.
- Disease and protein-specific filtering for targeted data extraction.
- Seamless integration with AlphaFold2 and ColabFold research workflows via Openclaw Skills.
SKILL.md
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Related Openclaw Skills
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Clarity Fold Status
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