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Official minimum-lambda variant of the Bohlin gestational-age LASSO: pyaging implements the 251-CpG lambda.min model and converts its day-scale output to weeks. The paper/package default one-standard-error variant uses 96 CpGs and has nearly identical predictive performance.
Predicts
gestational age
Species
Homo sapiens
Tissue
cord blood
Data type
DNA methylation
Model type
LASSO regression
Year
2016
Use with pyaging
import pyaging as pya
pya.pred.predict_age(adata, ["bohlin"])
Bohlin, J., Håberg, S. E., Magnus, P. et al. Prediction of gestational age based on genome-wide differentially methylated regions. Genome Biology 17, 207 (2016).
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