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Hypomethylation component of epiCMIT: a 1,164-CpG score ranging from 0 to 1 that tracks low-to-high relative proliferative history in normal and neoplastic B cells.
Predicts
mitotic age
Species
Homo sapiens
Tissue
B cells
Data type
DNA methylation
Model type
complement of mean methylation
Year
2020
Use with pyaging
import pyaging as pya
pya.pred.predict_age(adata, ["epicmithypo"])
Duran-Ferrer, M., et al. "The proliferative history shapes the DNA methylome of B-cell tumors and predicts clinical outcome." Nature Cancer 1 (2020): 1066-1081.
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