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CpGPTGrimAge3 implementation combining chronological age, GrimAge2 DNAm proxies, and CpGPT-predicted plasma-protein proxies in a Cox linear predictor that is calibrated to years.
Predicts
biological age, mortality risk
Species
Homo sapiens
Tissue
whole blood
Data type
DNA methylation
Model type
Cox proportional hazards regression
Year
2024
Use with pyaging
import pyaging as pya
pya.pred.predict_age(adata, ["cpgptgrimage3"])
de Lima Camillo, L. P., Sehgal, R., Armstrong, J., Higgins-Chen, A. T., Horvath, S., & Wang, B. CpGPT: a foundation model for DNA methylation. bioRxiv 2024.10.24.619766 (2024).
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